University Medicine Rostock (www.med.uni-rostock.de) is the maximum care hospital in the region of Rostock, a high potential growth region.
The Translational Neurodegeneration Section "Albrecht Kossel" at the Department of Neurology is investigating the mechanism of physiological and pathological aging as well as the pathophysiology of neurodegeneration. Aiming for the translation of innovative therapies into the clinical neurology, the main focus of the group is the application of human cell models of pathological aging (progeria infantilis and adultorum, down-syndrome), of adult neurodegeneration (ALS/FTD) and of juvenile neurodegeneration (NBIA, chorea-acanthocytosis, Niemann pick type C, NCL). We want to combine the strategies of reducing pathological aging on the one side and the specific therapy of neurodegeneration on the other side.
We are currently looking for a PhD student (f/m/d) to start as soon as possible, initially limited to 1,5 years as a E13 65% (26h/week) position paid according to TV-L.
Your tasks and perspective:
The main focus of the project concerns the assessment of the reasons and consequences of mitochondrial dysfunction in amyotrophic lateral sclerosis (ALS). Using iPSC disease modeling and broad range of molecular biology tools, cutting edge electrophysiology, live cell imaging techniques, you will try to understand the molecular pathophysiology of ALS.
Requirements:
The successful candidate should have a Master or equivalent degree in biological sciences and should be proficient in molecular and cell biology techniques such as human cell culture, PCR, molecular cloning, transfection, lentiviral vectors, western blot, immunofluorescence, Previous experience in the field of neuroscience is desirable. Publications in international peer reviewed journals and active participation in conferences are advantageous. Written and spoken English language proficiency, knowledge of Word, Excel, PowerPoint, Fiji and biomedical statistics are mandatory.
What we offer:
Spatial, technical and personal prerequisites for innovative research using cutting edge techniques within a motivated and cooperative group, which is well connected with local, national and international groups and clinicians. Possibilities to participate in further education courses, scientific meetings and habilitation are explicitly supported.
Proof of measles immunity: Please note that due to legal regulations, we can only hire applicants who are immune to measles. You must provide the relevant proof.
Severely disabled applicants will be given preferential treatment when filling vacancies within the framework of the applicable legal provisions if they are equally suitable.
Costs incurred in connection with the application cannot be covered.
